Commentary: Is a second booster for COVID-19 the right choice for you?

The Food and Drug Administration and the Centers for Disease Control and Prevention recently authorized a second booster shot of the Pfizer/BioNTech and Moderna COVID-19 vaccines for those age 50 and older. The recommendation follows a study out of Israel recently published in The New England Journal of Medicine. The Israel study reports a modest relative risk reduction in COVID-19 infections for those receiving a second booster compared to those who have gotten one booster, on the order of 1.5 times lower, with this benefit waning over the length of the study period, or around two months.